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Figure 2 With respect to skin, keratinocyte death by ferroptosis plays a remarkable role in driving skin inflammation after UVB exposure ( LN is one of the most severe organ manifestations of lupus, which most patients would develop within 5 years of SLE diagnosis ( For cardiovascular system, the oxidation of low-density lipoproteins (oxLDL) by ROS and the activation of endothelial cells in the artery, are recognized as initiation of atherosclerosis in SLE ( Conclusion and Perspectives In conclusion, ferroptosis is speculated to be an integral component in the vicious cycle of immune dysfunction, inflammation, and tissue damage in lupus

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Grupa kontrolna nie otrzymała dawki peptydu, otrzymując sól fizjologiczna