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Via the integration of GST inhibitor screening, enzyme inhibition kinetics, and molecular modeling approaches, they identified that 2,2′-dihydroxybenzophenones 6 and 8, as well as the N-acyl hydrazone analogues 14 and 16, exhibited satisfactory inhibitory potencies (IC 50(6) = 1.77 ± 0.10 μM
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Richard Russell Igor Z Barjaktarevic, 1 Aaron P Milstone 2 1 Division of Pulmonary and Critical Care Medicine, David Geffen School of Medicine at UCLA, Los Angeles, CA, USA
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