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[DOI] [PubMed] [Google Scholar] 180.Lee JY, Choo JE, Park HJ, Park JB, Lee SC, Jo I, et al
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Genetic factors add complexity to copper-targeted interventions: Polymorphisms in the ATP7B gene may impair hepatic copper excretion, leading to systemic copper overload, and mutations in APP can alter the copper-binding affinity of Aβ, thus influencing plaque formation and its neurotoxicity (255)
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