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A detailed analysis revealed that the SOD-2 subunit needs one metal atom and that it is functionally disabled in the absence of Mn atoms in the active site
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conducted metabolomic analysis of 17 primary glioblastoma multiforme (GBM) tumours, xenograft tumours derived from a series of GBM lines and a 50 GBM tumour metabolomic dataset, which overall showed no significant difference in MTA levels between MTAP -negative and MTAP -positive primary tumours (102)
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