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Tesamorelin is an FDA-approved synthetic growth hormoneโreleasing hormone analogue that stimulates IGF-1 production to reduce visceral abdominal fat in HIV-associated lipodystrophy, though its use outside this population remains unproven
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Compared with traditional drugs that block signaling pathways 8 , chimeric antigen receptor (CAR)-T therapy has shown promising prospects for the treatment of fibrosis 9
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