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This distinguishes it from GLP-1 medications, which in some patients have been associated with significant lean mass reduction alongside fat loss
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Key Clinical Significance Succinylcholine-induced hyperkalemia is most dangerous in patients with: Major burns Neuromuscular disorders (e.g., Duchenne or Becker muscular dystrophy) Severe trauma with muscle injury Prolonged immobilization Significant denervation injuries Because of the risk of fatal cardiac arrhythmias, succinylcholine should be avoided in these high-risk populations , and alternative neuromuscular blocking agents such as rocuronium are often preferred (Hovgaard & Juhl-Olsen, 2021
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