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Interestingly, in tumorigenesis these enzymes protect from cancer development but once this fails GSTs are essential for ensuring the survival of tumor cells [91]
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Aspirin-induced apoptosis in HepG2 cells As shown in Figure 2 (i), the apoptosis assay by flow cytometry has demonstrated that increasing doses of ASA treatment in GSH- depleted cells caused increased apoptosis in HepG2 cells
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