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Similarly, mutations in the Foxp3 gene, which controls Treg development, cause IPEX syndrome, a devastating autoimmune condition affecting multiple organ systems
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mGluR6 binds the glutamate from photoreceptors and activates the G protein G o , which leads to the closing of the cation channel TRPM1 (Transient Receptor Potential Cation Channel Subfamily M Member 1), therefore hyperpolarizing the neuron [151,152,153]
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