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ApoE isoforms affect neuronal N-methyl-D-aspartate calcium responses and toxicity via receptor-mediated processes
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Size:50 ml/1.69 fl.oz
This overactivation causes an influx of calcium ions into neurons, which, in turn, activates calcium-dependent enzymes, such as calpain, nitric oxide synthase and phosphatase, resulting in the degradation of cytoskeletal proteins and damage to cell membranes
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